Pollustop for Anti-Pollution (strong in vivo, ex vivo and in vitro data)
The stratum corneum layer of the skin is a protective barrier between the body and its environment. In addition to the damage caused to skin by UV light, atmospheric pollutants in our daily environment must also be considered as a major source of cutaneous stress. Over the past few years, lifestyle changes and increasing urbanisation worldwide have amplified the issue of pollution damage to the skin. Skin cells (the lipid and protein components, and DNA) are major targets for pollutants, which generate oxidation and inflammation. This can lead to premature ageing, acne, irritable and sensitive skin, atopic dermatitis and eczema, dry skin, redness and itching.
How deeply pollutants are absorbed into skin depends on the nature of the pollutant and the condition of the outer epidermis. Prolonged, repetitive exposure to high levels of pollutants overwhelms the skin's natural defence capabilities, causing the barrier to weaken and damage to spread. It is possible to increase the skin's protective ability by providing a shield that "breathes" and acts like a second skin. This keeps pollutants from being absorbed and thus reduces the damage they cause.
Pollustop (Biosaccharide Gum-4) is a de-acetylated, branched polysaccharide with a high molecular weight, which forms a non-occlusive film on the skin and hair. It forms a non-selective matrix and builds a protective barrier against the types of pollution that make up our daily environment. In this way, it can help to limit intra- and extracellular damage. The protection offered by Pollustop is physical and immediate, and is designed to prevent the appearance or aggravation of premature ageing and cutaneous disorders linked to pollution.
Pollustop is supported by strong and plentiful test data:
- In vivo: Evaluation of carbon particle (149 μm) and heavy metal encrustation
- In vitro: Evaluation of intracellular oxidative stress and mitochondrial stress induced by PM2.5 particles
- In vitro: Evaluation of cellular toxicity induced by cadmium
- In vitro: Evaluation of cellular toxicity, apoptosis and inflammation induced by UV radiation
- In vivo: Optimization of SPF
- Ex vivo: Evaluation of free radicals induced by UV radiation on hair
- In vitro: Evaluation of cellular toxicity induced by SDS
Pollustop: Aqua, Biosaccharide Gum-4, 1,2-Hexanediol. Glycofilm 1.5P: Version preserved using Phenoxyethanol.
Pollustop is the ideal ingredient to use in personal care formulations that protect against pollution. Please contact us to request your sample and further information about Pollustop today!