New data: Superox-C Maximises The Global Effect of Vitamin C

Southern Cross Botanicals have recently carried out some new studies to demonstrate that Superox-C induces stimulation of the Vitamin C transporter SVCT-I in human keratinocytes.

Vitamin C plays an essential role in keeping the skin young and healthy. This potent active molecule is well-known for its multiple actions. It is a strong antioxidant which protects the skin from oxidative stress by neutralising free radical-induced skin damage. Vitamin C also induces collagen biosynthesis in both young and aged skin. Vitamin C is also an anti-inflammatory agent known to prevent post-inflammatory hyperpigmentation and exert a brightening effect by interrupting the key steps of melanogenesis.

All of these remarkable effects rely on the skin’s capacity to transport Vitamin C through the skin’s layers. Sodium-dependent Vitamin C Transporter Type-I (SVCT-I), which is mainly expressed on the cell membrane of keratinocytes, plays a crucial role in the Vitamin C distribution across the epidermal layers and down to the dermis.

Advanced studies show that SVCT-I’s efficacy is very sensitive to environmental stress. It has been reported that UV radiation dramatically decreases SVCT-I expression and Vitamin C distribution. Therefore it is important to increase SVCT-I expression for healthy, radiant skin.

From Southern Cross Botanicals’ new studies, it was found that Superox-C dose-dependently stimulates the synthesis of SVCT-I in keratinocytes. Following 24 hours of incubation in the presence of Superox-C, SVCT-I expression was increased by +38% at 0.1% Superox-C and +106% at 0.2% Superox-C. By stimulating SVCT-I, Superox-C improves skin absorption of the Vitamin C which helps to maximise its efficacy.

Contact us to find out more, and request your sample of Superox-C today!